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Khan, M

Rather than reflecting a simple imbalance between energy intake and expenditure, obesity represents an actively defended physiological state in which compensatory mechanisms promote weight regain following weight loss attempts ( Among these strategies, glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as the most effective anti-obesity pharmacotherapies to date

In 2025, the weight management market is crowded with probiotics, fiber blends, fat burners, and GLP-1 drug alternatives